Prof. Thomas Krieg is a University Lecturer in Clinical Pharmacology and an Honorary Consultant Physician in Cambridge University Hospital. His research is directed toward identifying therapies that prevent cell death in ischemic heart and to understand the complex signal transduction pathways involved. Prof. Krieg and his team study these pathways using a model mirroring the pathophysiological events during an acute heart attack where we measure tissue death after a standardized ischemic insult as an end-point. Then they use pharmacological tools to both trigger and block the protection at specific points in the given pathway.
Prof. Thomas Krieg researches also isolated heart muscle cells as well as isolated mitochondria where protection can be analyzed with certain techniques and the chemical signals can be measured directly using protein chemistry.